Story at-a-glance
- Copper is essential for brain health, but having too much also leads to neurodegeneration and neurological disorders; maintaining balanced copper levels is essential to prevent oxidative stress and maintain cellular health
- Copper deficiency disrupts iron recycling and mitochondrial function, affecting enzymes crucial for glucose and antioxidant metabolism
- Mitochondrial dysfunction is a key factor in copper-induced neurotoxicity, with copper overload disrupting mitochondrial fusion and fission, leading to impaired energy production and increased oxidative stress
- Proper copper and iron balance is vital for overall metabolic health, as imbalances disrupt iron homeostasis and contribute to mitochondrial dysfunction and neuronal damage
- Strategies for addressing copper-related disorders include using mitoprotective agents to prevent copper neurotoxicity and ensuring adequate copper intake through diet or supplements to support mitochondrial function and iron metabolism
Copper’s dual role in brain health and neurotoxicity is a fascinating yet complex topic. While copper is necessary for brain development and function, having excessive amounts also leads to serious issues. In this article, we’ll discuss the benefits of copper and how it’s used in your body, but why an overload is also dangerous to your health, especially your brain.